Hotels in Saint Charles

Best Saint Charles Hotels

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15 Best Hotels to Stay in Saint Charles

Trip.com brings you a curated list of top accommodations in Saint Charles, complete with reviews, price insights, and amenity highlights, making it easy to find the perfect place to stay.
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Closest to Downtown
Highest Rated
Ameristar Casino Resort and Spa Hotels in Saint Charles
Ameristar Casino Resort and Spa Hotels in Saint CharlesAmeristar Casino Resort and Spa Hotels in Saint CharlesAmeristar Casino Resort and Spa Hotels in Saint CharlesAmeristar Casino Resort and Spa Hotels in Saint CharlesAmeristar Casino Resort and Spa Hotels in Saint CharlesAmeristar Casino Resort and Spa Hotels in Saint Charles
63
Hotels in Saint Charles
Golf course
Outdoor swimming pool
Casino
"My husband and I booked the King Deluxe, and upon inspecting the room, I can see that the furniture was not cleaned, it was old and dusty and had stains on it. The carpet looked like it hadn't been clean in years. The room had a bad smell to it, the bathroom area was pretty decent. I've stayed at Ameristar a few times, and I can honestly say, this was one of the worse experiences I had staying there. Ameristar PLEASE DO BETTER!"
Very Good
94 reviews
8.0/10
1 night
From THB 4,841
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Charming Studio Overlooking Cobblestone Street - Cozy Retreat Hotels in Saint Charles
Charming Studio Overlooking Cobblestone Street - Cozy Retreat Hotels in Saint CharlesCharming Studio Overlooking Cobblestone Street - Cozy Retreat Hotels in Saint CharlesCharming Studio Overlooking Cobblestone Street - Cozy Retreat Hotels in Saint CharlesCharming Studio Overlooking Cobblestone Street - Cozy Retreat Hotels in Saint CharlesCharming Studio Overlooking Cobblestone Street - Cozy Retreat Hotels in Saint CharlesCharming Studio Overlooking Cobblestone Street - Cozy Retreat Hotels in Saint Charles
30
Hotels in Saint Charles
Cozy studio apartment directly on Main Street in St. Charles MO. Windows that overlook the cobblestone street, and you can be on Main along the shops and restaurants in seconds! There is a full bathroom, kitchen space, and a King bed for you to make yourself at home! The unit has street parking only, and the staircase is shared with another short-term rental that we also operate. While the unit provides privacy, please note its proximity to bars and restaurants, where music can be heard in the evenings. Although we do not like fees in order to maintain our units we must make you aware of the following: We are ONLY dog-friendly.. . Strict NO SMOKING policy. If you smoke inside you will be fined $250. We are not responsible for items left behind by guests. If you leave an item behind and you want it to be sent back to you. We charge $25 for that item to be shipped plus the shipping costs. Any stay greater than 21 days will require an additional long-term cleaning fee of $50 that will be MANUALLY charged after reservation confirmation. An unapproved late check-out fine is $50. Minimum age to book this property is : 21
Amazing
9.7/10
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Cozy Clark Suite in Frenchtown Saint Charles Hotels in Saint Charles
Cozy Clark Suite in Frenchtown Saint Charles Hotels in Saint CharlesCozy Clark Suite in Frenchtown Saint Charles Hotels in Saint CharlesCozy Clark Suite in Frenchtown Saint Charles Hotels in Saint CharlesCozy Clark Suite in Frenchtown Saint Charles Hotels in Saint CharlesCozy Clark Suite in Frenchtown Saint Charles Hotels in Saint CharlesCozy Clark Suite in Frenchtown Saint Charles Hotels in Saint Charles
13
Hotels in Saint Charles
Stay comfortably in Saint Charles at this 1-bedroom apartment. The bedroom features a cozy king bed, perfect for a peaceful night's sleep. Enjoy the lovely living room with a comfy futon for extra relaxation. This charming space offers AC, WiFi, and other enjoyable amenities for guests. With a hair dryer and shower in the bathroom, your stay will be convenient and stress-free. You're sure to make fantastic memories with a stay at our place.About pets:Pets allowed: dogs less than 20 lbs per pet (limit one pet total).About checkOut:Check out before 10:00 AM.About children:Children allowed: ages 0-17.About checkIn:Check in after 4:00 PM.About smoking:Smoking is not permitted.About minBookingAge:Minimum age to rent: 18.About events:No events allowed.
Outstanding
9.9/10
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Western-Themed 2-Bedroom Hideout for Outlaws 204-2 Hotels in Saint Charles
Western-Themed 2-Bedroom Hideout for Outlaws 204-2 Hotels in Saint CharlesWestern-Themed 2-Bedroom Hideout for Outlaws 204-2 Hotels in Saint CharlesWestern-Themed 2-Bedroom Hideout for Outlaws 204-2 Hotels in Saint CharlesWestern-Themed 2-Bedroom Hideout for Outlaws 204-2 Hotels in Saint CharlesWestern-Themed 2-Bedroom Hideout for Outlaws 204-2 Hotels in Saint CharlesWestern-Themed 2-Bedroom Hideout for Outlaws 204-2 Hotels in Saint Charles
25
Hotels in Saint Charles
2 bedroom/1 bathroom western themed unit located just a short walk from the historic Main Street district. are ONLY dog friendly. Please note this unit is above a bar with live music and it shares the back patio. We weren't kidding when we said you were steps away from all the action! Dog friendly only. A $100 pet fee will be manually requested AFTER booking if your dog/s will be joining you.About pets:Pets allowed: dogs less than 20 lbs per pet (limit one pet total).About checkOut:Check out before 10:00 AM.About children:Children allowed: ages 0-17.About checkIn:Check in after 4:00 PM.About smoking:Smoking is not permitted.About minBookingAge:Minimum age to rent: 20.About events:No events allowed.
Great
9.2/10
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3BR Historic St. Charles, MO-Walking distance to Main Street Hotels in Saint Charles
3BR Historic St. Charles, MO-Walking distance to Main Street Hotels in Saint Charles3BR Historic St. Charles, MO-Walking distance to Main Street Hotels in Saint Charles3BR Historic St. Charles, MO-Walking distance to Main Street Hotels in Saint Charles3BR Historic St. Charles, MO-Walking distance to Main Street Hotels in Saint Charles3BR Historic St. Charles, MO-Walking distance to Main Street Hotels in Saint Charles3BR Historic St. Charles, MO-Walking distance to Main Street Hotels in Saint Charles
25
Hotels in Saint Charles
Wi-Fi in public areas
Welcome to your perfect getaway! This charming 3-bedroom, 3-bathroom house is the ideal spot to relax and recharge during your stay in St. Charles, Missouri. Just a short walk to historic Main Street, you’ll have easy access to unique shops, great restaurants, and local attractions. If you're visiting the area for school, Lindenwood University is also nearby.Step inside, and you’ll find a fully updated kitchen with everything you need to feel right at home, including a full set of appliances. The open-concept dining and living area offers a welcoming space for family gatherings or a quiet evening in. For a little fun, you can challenge your group to a game of air hockey or settle in for a movie night on the Smart TV.After a busy day of exploring, relax on the front porch and enjoy the serene surroundings. Whether you’re here for a vacation, family visit, or work trip, this home has everything to make your stay comfortable and convenient.With 3 king-sized beds and 3 full bathrooms (each with a shower or tub combo), there’s plenty of space to spread out. One of the bedrooms and bathrooms is conveniently located on the main level for easy access.About pets:No pets allowed.About children:Children allowed: ages 0-17.About smoking:Smoking is not permitted.About events:No events allowed.
Very Good
13 reviews
8.0/10
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Holiday Inn Express & Suites ST Charles Hotels in Saint Charles
Holiday Inn Express & Suites ST Charles Hotels in Saint CharlesHoliday Inn Express & Suites ST Charles Hotels in Saint CharlesHoliday Inn Express & Suites ST Charles Hotels in Saint CharlesHoliday Inn Express & Suites ST Charles Hotels in Saint CharlesHoliday Inn Express & Suites ST Charles Hotels in Saint CharlesHoliday Inn Express & Suites ST Charles Hotels in Saint Charles
99+
Hotels in Saint Charles
Indoor swimming pool
Gym
Private parking
"Nice location!"
Very Good
94 reviews
8.2/10
1 night
From THB 4,996
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The Wild West Getaway- 204-1 Hotels in Saint Charles
The Wild West Getaway- 204-1 Hotels in Saint CharlesThe Wild West Getaway- 204-1 Hotels in Saint CharlesThe Wild West Getaway- 204-1 Hotels in Saint CharlesThe Wild West Getaway- 204-1 Hotels in Saint CharlesThe Wild West Getaway- 204-1 Hotels in Saint CharlesThe Wild West Getaway- 204-1 Hotels in Saint Charles
18
Hotels in Saint Charles
Welcome to Cowboy, our charming, 2 bedroom/1 bathroom apartment located in the heart of historic St. Charles. Saddle up and come experience all main street has to offer. (Please note this unit is above a bar with live music and it shares the back patio. We weren't kidding when we said you were steps away from all the action!) We are ONLY dog friendly. A $100 pet fee will be manually charged AFTER booking if your dog/s will be joining you.About pets:Pets allowed: dogs less than 50 lbs per pet (limit one pet total).About checkOut:Check out before 10:00 AM.About children:Children allowed: ages 0-17.About checkIn:Check in after 4:00 PM.About smoking:Smoking is not permitted.About minBookingAge:Minimum age to rent: 18.About events:No events allowed.
Very Good
5 reviews
8.4/10
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Hampton Inn by Hilton St. Charles St. Peters Hotels in Saint Charles
Hampton Inn by Hilton St. Charles St. Peters Hotels in Saint CharlesHampton Inn by Hilton St. Charles St. Peters Hotels in Saint CharlesHampton Inn by Hilton St. Charles St. Peters Hotels in Saint CharlesHampton Inn by Hilton St. Charles St. Peters Hotels in Saint CharlesHampton Inn by Hilton St. Charles St. Peters Hotels in Saint CharlesHampton Inn by Hilton St. Charles St. Peters Hotels in Saint Charles
75
Hotels in Saint Charles
Public parking
Gym
24-hour front desk
"Hampton Inns usually have great locations to surrounding areas. I needed to travel between both towns in between, great stay."
Very Good
97 reviews
8.0/10
1 night
From THB 3,863
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Sleep Inn Hotels in Saint Charles
Sleep Inn Hotels in Saint CharlesSleep Inn Hotels in Saint CharlesSleep Inn Hotels in Saint CharlesSleep Inn Hotels in Saint CharlesSleep Inn Hotels in Saint CharlesSleep Inn Hotels in Saint Charles
68
Hotels in Saint Charles
Private parking
Gym
24-hour front desk
Located in St. Charles, Sleep Inn & Suites is in the historical district, a 5-minute drive from Fast Lane Classic Cars and 6 minutes from Lindenwood University. This hotel is 4.3 mi (7 km) from Historic Main Street and 5.4 mi (8.7 km) from Lewis & Clark Boathouse and Nature Center. Take advantage of recreation opportunities such as an indoor pool, or other amenities including complimentary wireless internet access and a television in a common area. A complimentary buffet breakfast is served daily from 6:00 AM to 9:00 AM. Featured amenities include a business center, a 24-hour front desk, and laundry facilities. Free self parking is available onsite. Make yourself at home in one of the 70 guestrooms featuring refrigerators and flat-screen televisions. Complimentary wireless internet access keeps you connected, and cable programming is available for your entertainment. Conveniences include safes and desks, as well as phones with free local calls.
96 reviews
5.8/10
1 night
From THB 2,619
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Spacious Dining and Walkable Shopping District - Charming Historic Haven Hotels in Saint Charles
Spacious Dining and Walkable Shopping District - Charming Historic Haven Hotels in Saint CharlesSpacious Dining and Walkable Shopping District - Charming Historic Haven Hotels in Saint CharlesSpacious Dining and Walkable Shopping District - Charming Historic Haven Hotels in Saint CharlesSpacious Dining and Walkable Shopping District - Charming Historic Haven Hotels in Saint CharlesSpacious Dining and Walkable Shopping District - Charming Historic Haven Hotels in Saint CharlesSpacious Dining and Walkable Shopping District - Charming Historic Haven Hotels in Saint Charles
26
Hotels in Saint Charles
The original Customs House in St. Charles, MO. You'll love this charming and historic property. Large enough for 6 adults to sleep comfortably, and two separate bedrooms. Stocked Kitchen with a Large Dining Table. Perfect to enjoy a meal with friends and family or dine out on many of the walking distance restaurants and cafes. Centrally Located on Main Street, with plenty of shopping and dining all within walking distance. Be sure to check it out! Although we do not like fees to maintain our units we must make you aware of the following: We are ONLY dog-friendly.. . Strict NO SMOKING policy. If you smoke inside you will be fined $250. We are not responsible for items left behind by guests. If you leave an item behind and you want it to be sent back to you. We charge $25 for that item to be shipped plus the shipping costs. Any stay greater than 21 days will require an additional long-term cleaning fee of $50 that will be MANUALLY charged after reservation confirmation. An unapproved late check-out fine is $50. Minimum age to book this property is : 21
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Immerse yourself in the vibrant atmosphere of Saint Charles with our handpicked accommodation options

FAQs About Saint Charles Hotels

What are some of the best hotels in Saint Charles?

Whether you're planning a business trip or a vacation, Saint Charles has many top-rated hotels to choose from. Ameristar Casino Resort and Spa (price from THB 5,252), Sleep Inn (price from THB 2,532) and Holiday Inn Express & Suites ST Charles (price from THB 4,721) are among the best choices for your stay.

How to get good deals on hotels in Saint Charles?

Find the best hotel deals and promotions on Trip.com, available year-round for both first-time and loyal users. Please check the promotions page to see what promotions are available now on Trip.com.

What are the best hotels with a spa in Saint Charles?

A spa hotel can make your trip more enjoyable with relaxing amenities. Ameristar Casino Resort and Spa (price from THB 5,252) is one of the best hotels with a spa in the area.

Which hotels in Saint Charles provide fitness facilities?

Ameristar Casino Resort and Spa (price from THB 5,252), Sleep Inn (price from THB 2,532) and Holiday Inn Express & Suites ST Charles (price from THB 4,721) include fitness facilities, so you can maintain your routine while traveling. Stay on track with your fitness goals while on the go!

Which hotels in Saint Charles have pools?

Ameristar Casino Resort and Spa (price from THB 5,252), Sleep Inn (price from THB 2,532) and Holiday Inn Express & Suites ST Charles (price from THB 4,721) are excellent options for hotels with swimming pools. Book your stay to enjoy the pool and make your trip more enjoyable.

What hotels in Saint Charles offer an especially good breakfast?

Begin your day with a tasty and satisfying breakfast! Holiday Inn Express & Suites ST Charles (price from THB 4,721), Sleep Inn (price from THB 2,532) and Hampton Inn by Hilton St. Charles St. Peters (price from THB 2,856) provide the best breakfast to start your day.

What are some good hotel options near St. Charles Historic District in Saint Charles?

Based on traveler reviews, some of the top-rated hotels near St. Charles Historic District in Saint Charles include Ameristar Casino Resort and Spa (price from THB 5,252), Candlewood Suites ST. Louis - ST. Charles (price from THB 2,664) and Sleep Inn (price from THB 2,532), all known for their excellent service and prime locations.

What are the must-see spots in Saint Charles?

Saint Charles is packed with incredible must-see landmarks, like St. Charles Historic District.

Saint Charles Hotels Info

Highest PriceTHB 17,100
Number of Reviews 406
Total Properties15
Average Price(Weekday Night)THB 5,016
Average Price(Weekend Night)THB 6,009